In many areas of the Mediterranean, projects are emerging with the aim of developing rural communities by promoting natural resources and local expertise. Strengthening agricultural know-how means consolidating a wealth of knowledge which, when shared and continuously updated, promotes sustainable practices, stimulates innovation and generates new economic, social and entrepreneurial opportunities. In Haouaria, Tunisia, this approach has taken the form of a pilot bio-territory, designed as an integrated local development system that combines agricultural production, services, entrepreneurship, creativity and innovation, promoting micro and small businesses, local supply chains and the responsible use of natural resources.