Geoinformation solutions applied to precision agriculture provide effective support for agronomic techniques aimed at a more informed management of crop life cycles. In the Po Valley, one of Europe’s largest and most productive agricultural areas, multi-source images from Space provide up-to-date data for analyses that support the complex food production chain, integrating multi-temporal observations, technology and thematic knowledge. By combining Earth observation data, advanced Big Data and Artificial Intelligence it is possible to track the phenological cycle and to generate vegetation indices and biophysical parameters, thereby promoting productivity, cost reduction and soil protection.